Syrian Rue: Everything You Need To Know
Syrian rue, scientific name Peganum Harmala, is a perennial shrub native to the Mediterranean and various regions of Asia. It can now also be found growing wild on the American continent. Part of the Nitrariaceae plant family, Syrian rue can grow up to 1m, but in the wild rarely gets above 0.3m in height. It has narrow leaves that are usually 5 cm long when fully grown and produces many single white flowers.
The seeds of Syrian rue are of most interest, as they contain the harmala alkaloids harmine and harmaline – highly psychoactive alkaloids that are sometimes used to potentiate other plants, although it is reported that harmala alkaloids are psychoactive by themselves. They also act as reversible MAO inhibitors (RIMAs), for which reason Peganum Harmala is commonly used to activate oral DMT.
The Effects Of Syrian Rue: Mao Inhibitors & Harmala Alkaloids
As previously mentioned, the alkaloids within the Syrian rue act as monoamine oxidase inhibitors (MAOIs), respectively as reversible MAO inhibitors (RIMAs). There is a ongoing debate as to wether RIMAs require the same tyramine restriction in diet as MAOIs, but the final judgement is still out. As it stands, we can only advise to closely follow the MAOI diet prior to the consumption of Syrian rue seeds. For a detailed list of the MAOI-diet, click here.
As Syrian rue is an MAOI, it is very commonly used to potentiate other psychedelic plants, enhancing them and prolonging the high. A good example of this is the use of magic mushrooms or DMT, where the prior use of Syrian rue is reported to lengthen the experience by up to 4 hours. Syrian rue can also be used as a psychedelic itself with larger doses, but this can cause an unpleasant feeling. Anecdotal reports describe how pure harmala alkaloids of the rue can result in a range of hallucinogenic effects, from closed eye visuals, all the way to open eyed patterns and distortions.
Traditional Use Of Peganum Harmala
Syrian rue has many traditional uses across the Middle East and parts of Asia, having influenced religion, industry and local folklore.
In Afghanistan, Iran, Iraq, Uzbekistan, Azerbaijan, Tajikistan and Turkey the dried capsules of the Syrian rue seeds are mixed with other ingredients and placed on hot coals. This causes them to explode and release fragrant, incense-like smoke. It is during this process that prayer is recited.
In Turkey, it is believed that the dried capsules of the plant can be strung up within the home to protect against “the evil eye”, a malevolent look that is thought in many cultures to cause injury or misfortune to those who were subjugated to it. In Morocco it is believed to offer protection from djinn.
The seeds of Syrian rue are used as a traditional way of making dye throughout the Middle East.
As Syrian rue is an MAOI, it is very commonly used to potentiate other psychedelic plants, enhancing them and prolonging the high. A good example of this is the use of magic mushrooms or DMT
Syrian Rue seeds
Syrian rue(peganum harmala)
Amount: 10 gram
Dose: 2 doses
Ingredients: The primary active ingredients in P. harmala are harmine and harmaline.
Effect: Common use of Syrian rue has the effect of a psychopharmacological tool, making otherwise inactive plants active. Sometimes Syrian rue is used to strengthen and prolong the effects of substances that are active by themselves. Syrian rue prevents the breakdown of monoamine neurotransmitters by inhibiting the action of monoamine oxidase enzymes, a process known as MAO-inhibition. This renders substances like DMT and 5-MeO-DMT orally active and makes a psilocybin mushroom experience last longer and become stronger. A small number of people is experimenting with the effects of only Syrian rue infusions or smoked seeds. The effects of low doses are sometimes referred to as ‘the harmala buzz’, as it tends to cause a buzzing feeling throughout the head and body. This is also the initial stage for most people taking a higher dose, though it generally unfolds into a stronger experience associated with nausea, stomach cramps and vomiting. Also, psychedelic effects, such as visual and auditive distortions and mystical phenomena, seem to be common for some people.
How to use: It is possible to consume the seeds directly, by grinding them with your molars. Let the ground seeds have interplay with your saliva for half a minute up to a couple of minutes and swallow. Another way is to grind the seeds with a morter and put the powder in gelcaps. With these methods none of the active ingredients gets lost in the preparation process. For a Syrian rue only experience, doses are still experimental. People should start with 1 gram to see how they react. 5 grams is a high dose for most people. For potentiating a normal or high dose of oral DMT, taking 3 grams of seeds 15 to 60 minutes prior to the DMT is an established method. Taking more usually results in more physical discomfort and no stronger effect. The experience will last around 4 hours. The same method can be used prior to eating mushrooms, which will make the mushrooms 1½ to 2 times stronger. It also adds 1 to 3 hours to the duration. Another common preparation method, which is easier on the stomach and causes less nausea in general, is to make a hot water infusion. Part of the active ingredients can easily get lost in the process of this method, so add 1 to 2 grams to the doses mentioned earlier. 150 ml of water and 50 ml of lemonjuice per person is used. Simmer the finely ground seeds for 15 to 30 minutes on the lowest fire on your stove and strain the liquid, which is then ready for consumption. And finally, many people still use these seeds as an incense. In high amounts this can also cause MAO-inhibition, albeit of shorter duration in comparison with oral ingestion.
Warning: Peganum harmala contains MAO-inhibiting substances. This means it can be very dangerous when combined with certain foods or other psychoactives that are totally harmless when taken by themselves.
Syrian Rue seeds Description Syrian rue(peganum harmala) Amount: 10 gram Dose: 2 doses Ingredients: The primary active ingredients in P. harmala are harmine and harmaline.