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Can You Use Kratom for Depression and Anxiety?

Kratom is a tropical tree native to South Asia. Kratom leaves or extract from its leaves have been used in alternative medicine for chronic pain and other conditions.

Many people also use kratom to self-treat symptoms of depression or anxiety.

Although some evidence suggests that certain strains of kratom can help alleviate these symptoms, more research is needed.

The U.S. Food and Drug Administration (FDA) hasn’t approved kratom for the treatment of depression or anxiety.

Kratom is considered a dietary supplement, so it isn’t regulated by the FDA.

If you’re thinking about using kratom to treat depression or anxiety symptoms, exercise caution.

Read on to find out more about the purported benefits and potential risks.

Kratom isn’t technically an opioid, but its effects are similar to those of opioids, such as morphine or codeine.

The active ingredient in kratom is called mitragynine. Mitragynine binds to opioid receptors in the brain, relieving pain.

This action might be behind the antidepressant and anti-anxiety effects reported by some kratom users.

There’s currently very little research on kratom’s effects on mood.

One 2017 review confirmed that among some users, kratom enhances mood and relieves anxiety.

The researchers also highlighted that kratom can have sedative effects. Researchers have yet to examine whether side effects such as sedation can interfere with its purported benefits.

In addition to depression and anxiety, kratom is said to treat the following conditions:

  • pain
  • muscle aches
  • fatigue
  • high blood pressure
  • opioid addiction and withdrawal
  • diarrhea
  • post-traumatic stress disorder (PTSD)

According to a 2017 review , other studies report that kratom also has anti-inflammatory, immunity-enhancing, and appetite-suppressing effects.

More research is needed to confirm these benefits.

Kratom (Mitragyna speciosa) is a tree found in parts of Southeast Asia, including Thailand and Malaysia.

Kratom’s active ingredient, mitragynine, is found in its leaves.

At lower doses, mitragynine has energizing effects. At higher doses, it has sedative effects.

In parts of Southeast Asia, people have been using kratom for centuries. Other names for kratom include:

  • biak
  • kakum/kakuam
  • ketum
  • thang
  • thom

Kratom is illegal in many countries around the world, including Australia, Thailand, and Denmark.

Although it’s legal in the United States, there have been efforts to restrict access to and regulate the substance.

Kratom can be ingested in a variety of forms, including:

  • capsules
  • tablets
  • gum
  • tinctures
  • extracts

In some cases, kratom leaves are eaten fresh or dried, or boiled and consumed as a tea.

Dried leaves can also be ground up into a powder and ingested.

Kratom can be smoked or vaporized, though this is less common.

The method of ingestion may influence kratom’s effects. However, there’s currently no research identifying which method is preferable in treating depression and anxiety.

Different types of kratom are called strains. Most kratom strains take their names from their places of origin.

As with marijuana strains, different kratom strains have slightly different effects.

There’s currently no research into the effects of different strains of kratom. The following descriptions are based only on anecdotal reports.

It’s also worth noting that the effects of a particular strain might vary from one supplier to another.

Maeng da

Maeng da refers to several different types of purportedly strong and long-lasting kratom.

Maeng da originated in Thailand, but Indonesian and Malaysian maeng da strains are also available. Maeng da can be green, red, or white in color.

It’s said to act as a stimulant, increasing energy while also inducing feelings of well-being and reducing pain. Some people report feeling talkative after taking maeng da.

Indo kratom comes from Indonesia. It can be green, red, or white in color.

Indo kratom is considered to be less stimulating than other strains, though some types may have mild energizing effects.

In general, Indo strains are known for increasing relaxation, relieving pain, and promoting feelings of well-being. They are thought to help with anxiety.

Bali/red vein

Bali kratom originates in Indonesia. It’s reddish in color and believed to provide effective pain relief.

Users say it’s the most “opioid-like” of all the kratom strains. It may help relieve pain-related conditions, such as depression or chronic pain.

Green Malay

Green Malay kratom comes from Malaysia. It’s dark green in color.

At low doses, it’s said to provide energy and focus along with pain relief. At high doses, it may have more of a sedative effect.

It’s said to help with anxiety.

Thai kratom comes from Thailand. Red, green, and white vein Thai kratom is available, and the effects may vary according to color.

Green and white vein strains are said to provide stimulation and create a euphoric “high.”

Red vein Thai kratom is said to provide pain relief.

Borneo

Borneo kratom comes from Borneo. It comes in red, green, and white vein varieties.

Compared to other strains, Borneo kratom is considered to have a more sedating effect. It may be used to treat anxiety and stress.

Malaysian

Malaysian strains, including green, red, and white vein kratom varieties, are said to provide a balance between stimulating and sedative effects.

Users report mood lifts, pain relief, and increased energy and focus.

Little is known about kratom dosage guidelines for depression and anxiety.

Generally speaking, the recommended dose depends on your age, sex, and health status. Other factors, such as the method of ingestion and the strain, can also influence kratom’s effects.

For example, kratom extract is considered to be significantly more potent than kratom powder.

In a 2018 study based on a survey of 8,049 people who use kratom, most people reported that a dose of up to 5 grams of powder taken up to 3 times per day was adequate to experience effects.

It’s recommended that you start with a low dose, gradually increasing the amount until you achieve the desired effect.

The following general guidelines indicate low to high doses for kratom powder, as well as kratom’s effects according to dose:

Category Dose Effects
Low to moderate 1 to 5 grams Increased energy and focus
High 5 to 15 grams – Pain relief
– Opioid-like “high”
– Increased risk of side effects
Risky > 15 grams – Sedation
– Increased risk of serious side effects

Kratom can have a variety of effects, depending on the individual, dosage, and other factors. Research into kratom’s effects is ongoing.

The following lists are based on the research that’s currently available, but may not be exhaustive due to their limited nature.

Effects on brain and behavior

Kratom may have the following mental, emotional, and behavioral effects:

  • increased focus
  • reduced anxiety
  • enhanced mood
  • euphoria
  • increased talkativeness

Effects on body

Kratom may have the following effects on your body:

  • increased energy
  • decreased pain
  • muscle relaxation

Kratom usually takes 5 to 10 minutes to take effect.

At low to moderate doses, kratom’s effects last around two hours. At higher doses, effects can last up to five hours.

Although kratom is well-tolerated by many people, side effects are possible.

Mild side effects may include:

  • dry mouth
  • itching
  • frequent urination
  • headache
  • constipation
  • drowsiness
  • dizziness
  • nausea
  • vomiting
  • mood changes

Severe side effects may include:

  • heart palpitations
  • high blood pressure
  • insomnia
  • loss of appetite
  • loss of libido
  • memory problems
  • kidney problems
  • liver problems
  • psychosis

In 2016, the Centers for Disease Control and Prevention (CDC) released a report indicating that out of 660 calls to poison control centers about kratom exposure, most reported side effects were minor or moderate.

Kratom may interact with other substances, including alcohol, leading to potentially life-threatening complications.

In rare cases, kratom overdose can lead to coma and death.

Stopping kratom use after a period of time is associated with withdrawal symptoms. This includes insomnia, mood swings, and nausea.

Withdrawal may exacerbate anxiety and depression.

A 2017 review concluded that the potential side effects of using kratom may outweigh the benefits.

If you’re thinking about taking kratom for depression or anxiety, take some time to learn about the risks.

Kratom may help relieve certain symptoms, but it may also have negative side effects. For some people, the benefits may not outweigh the risks.

If you decide to take kratom, proceed with caution. Start with a small dose so you can monitor its effects. Consider telling a trusted friend or loved one to check on you.

Remember that kratom can interact with other substances, including medication and alcohol. You shouldn’t drive or operate machinery after taking kratom.

If you experience severe side effects, discontinue use and seek medical attention.

Last medically reviewed on December 19, 2018

Many people use kratom to self-treat symptoms of depression or anxiety. Although some evidence suggests that certain strains can successfully help depression and anxiety symptoms, more research is needed. Here's how it's said to work, how it's used, and more.

Kratom for Relaxation: The Most Relaxing Kratom Strains Ranked

Mitragyna speciosa , better known as kratom, is a versatile plant. Depending on the strain and vein colors, it can deliver pain relief, a mood boost, or sedative effects. But one of the most popular uses is kratom for anxiety. But what is the most relaxing kratom?

In today’s article, we’re going to be going over the most common strains of kratom, so you can determine which vein colors meet your needs. Read on for this quick guide to the world’s best quality kratom and their effects!

Why Are Some Kratom Strains More Relaxing Than Others? One Word: Alkaloids

Like all botanicals, kratom is made up of a complex combination of natural chemical compounds. Of these compounds, some of the most important (and potent!) are known as alkaloids .

The various strains of kratom are actually all the same plant species. What distinguishes them from each other is their unique combination of kratom alkaloids. The unique alkaloid blend found in each of the red, white, and green vein colors determines both the strain’s effects and its color!

The two alkaloids believed to be most responsible for kratom’s effects are known as mitragynine and 7-hydroxymitragynine .

  • Mitragynine: Mitragynine is the more versatile of the two primary kratom alkaloids, and the “dosage-dependent” rule (see below) applies more heavily. This compound is highest in young plants, so white vein kratom strains contain the most mitragynine, followed by green vein, then red vein.
  • 7-hydroxymitragynine: 7-hydroxymitragynine is also dosage-dependent, but it tends to have more potent analgesic and sedative effects, making high 7-HO strains an ideal kratom for anxiety and relaxation. This compound is highest in mature plants, so red vein kratoms contain the most 7-hydroxymitragynine, followed by green vein, then white vein.

As the kratom plant grows and matures, its mitragynine levels gradually decrease while its 7-hydroxymitragynine levels gradually increase.

But Which is the Most Relaxing Kratom Alkaloid?

Both mitragynine and 7-hydroxymitragynine have the potential to relax users. They can both elicit sedative effects to varying degrees. However, there are some significant differences between kratom strains and their unique alkaloid profiles.

It’s important to keep in mind that kratom’s effects are dose-dependent. According to The Journal of the American Osteopathic Association ,

“Low to moderate doses (1-5 g) of the leaves reportedly produce mild stimulant effects that [. . .] stave off fatigue. Moderate to high doses (5-15 g) are reported to have opioid-like effects.”

Regardless of which vein colors you choose to use, this rule will hold true for most users. However, the unique alkaloid profile of each strain allows some to stand out as the most relaxing kratom strains.

Red Vein Kratom: the Most Relaxing Kratom

Red vein kratom is made from the most mature plants, harvested at the last stage of the kratom tree’s life-cycle. Red vein strains are very high in 7-hydroxymitragynine, which makes red vein strains the most relaxing kratom.

However, not all red vein strains are created equal. If you’re looking for the truly most relaxing kratom strain, consider the following:

  • Red Thai Kratom
  • Red Maeng Da Kratom

White Vein Kratom: the Most Uplifting and Energizing Kratom

White vein kratom is harvested from young plants whose 7-hydroxymitragynine levels are very low. Users looking for the most relaxing kratom should look elsewhere, but white vein strains certainly have their uses — and many devoted fans.

White vein strains are more uplifting and energizing, and they are generally considered the most uplifting strains of kratom. Like kratom’s cousin, coffee, green vein strains are great for an energy boost or to help you focus. But if you’re looking for something to relax or a strain of kratom for anxiety, you’d be better served by red vein or green vein strains and stay away from this energizing kratom strain.

Green Vein Kratom: the Middle of the Road

Green vein kratom is harvested in the middle of the kratom tree’s life-cycle, and it boasts a balance of kratom’s two main alkaloids.

The kratom community values green vein kratom strains for their “middle of the road” effects, balancing the energizing properties of white and the relaxing properties of red vein strains.

If you’re looking for the most relaxing kratom experience while also maintaining clear-headed energy, green vein strains may be the perfect option.

The Bottom Line on the Most Relaxing Kratom Strains

Ultimately, red vein kratom will have the most potent relaxing and anti-anxiety effects, but it can make some users feel sedated and lethargic.

If you’re looking for the most relaxing kratom strain that will still keep you feeling energized and focused, green vein strains may be the perfect option for you.

However, remember that all strains of kratom are dosage-dependent. Depending on the size of your kratom dose, you should expect to feel different effects.

Whenever you begin using a new strain of kratom, it’s always best to start small. This is particularly true of strains with higher-than-average alkaloid content, such as Maeng Da kratom .

Don’t be afraid to branch out! With a bit of experimentation, you’re sure to find the most relaxing kratom strain that fits best into your unique lifestyle!

Which strains of kratom are best for relaxation? Learn all about the world's best strains of kratom, with everything you need to pick the right one for you.